A scratch from a cat may seem minor, but if the skin becomes red, swollen, and painful, you may be developing cellulitis—a potentially serious skin infection. Cat scratches can introduce bacteria deep into the skin, and prompt, effective treatment is essential to prevent complications. Here’s what you should know about the best antibiotics for cat scratch cellulitis, how your doctor will choose the right one, and how to promote safe healing.
What Is Cellulitis?
Cellulitis is a bacterial infection of the deeper layers of the skin and underlying tissue. It often occurs after bacteria enter through a break in the skin—such as a cat scratch. While mild cases may cause redness and swelling, untreated cellulitis can spread rapidly, leading to fever, abscess, or even bloodstream infection.
- Symptoms: Redness, swelling, warmth, pain, and tenderness at the scratch site. Fever, chills, or streaking red lines are signs the infection is spreading.
- Common bacteria: Pasteurella multocida (most common from cats), Staphylococcus, and Streptococcus species.
Why Is Cat Scratch Cellulitis Different from Other Skin Infections?
Cats carry specific bacteria in their mouths and under their claws—especially Pasteurella multocida—which can cause cellulitis more rapidly than bacteria from many other animals. Symptoms often begin within hours to a couple of days of the scratch.
Best First-Line Antibiotic for Cat Scratch Cellulitis
Amoxicillin-clavulanate (Buy on Amazon) (brand name: Augmentin) is the most widely recommended oral antibiotic for cat-related cellulitis in adults and children.
- Why Augmentin? It effectively covers Pasteurella, Staph, Strep, and anaerobes—addressing all major bacteria from cat injuries.
- Dosing: Usually taken twice daily for 7–10 days (exact duration and dose depend on severity and patient factors).
- Results: Most people improve within 24–48 hours; finish the full course even if you feel better sooner.
Important: Always take antibiotics as prescribed by your doctor and never use leftover or someone else’s medication.
Alternatives for Penicillin-Allergic Patients
If you have a penicillin or amoxicillin allergy, let your healthcare provider know immediately. Effective alternatives may include:
- Doxycycline (Buy on Amazon) (often paired with metronidazole or clindamycin)
- Clindamycin (Buy on Amazon) plus a fluoroquinolone (like ciprofloxacin) or trimethoprim-sulfamethoxazole (TMP-SMX)
- Azithromycin or clarithromycin (for those who cannot tolerate the above; not always as effective against Pasteurella)
Your doctor will choose the combination that best fits your medical history and allergy profile.
What to Do If You Develop Cellulitis After a Cat Scratch
- Clean the wound immediately with soap and water.
- Apply an antiseptic and keep the area clean and dry.
- Monitor for symptoms: Redness, swelling, pain, warmth, pus, fever, or red streaks moving away from the site.
- Seek prompt medical attention if any of the above symptoms develop—cellulitis can worsen quickly.
- Follow all instructions for wound care and medication.
Frequently Asked Questions
How soon should antibiotics be started after a cat scratch causes cellulitis?
Antibiotics should be started as soon as cellulitis is diagnosed. The earlier the treatment, the lower the risk of serious complications.
Can I use Neosporin or other topical antibiotics alone?
Topical antibiotics are not enough for cellulitis, which is a deep skin infection. Oral (or sometimes intravenous) antibiotics are required for proper treatment.
What happens if cellulitis isn’t treated?
Untreated cellulitis can spread to deeper tissues, the bloodstream (sepsis), joints, or bones—potentially leading to hospitalization or even life-threatening complications.
Is hospitalization necessary?
Most cases of mild to moderate cellulitis can be treated with oral antibiotics at home. Hospitalization is only needed for severe infections, if oral antibiotics aren’t working, or if you have risk factors (such as immunosuppression, diabetes, or extensive skin involvement).
What about cat scratch disease (Bartonella henselae)?
While “cat scratch disease” is a different infection caused by Bartonella henselae, it usually presents as swollen lymph nodes and mild fever—not classic cellulitis. Treatment is different; your doctor will help distinguish between these if needed.
How to Prevent Cat Scratch Cellulitis
- Trim your cat’s claws regularly to reduce scratch severity.
- Never tease or rough-play with cats using your hands.
- Keep cats indoors to lower their exposure to outdoor pathogens.
- Supervise children with cats and teach gentle handling.
- Clean any scratches immediately and watch closely for signs of infection.
Conclusion: Act Quickly and Follow Medical Advice
Cat scratch cellulitis requires fast, effective treatment. Amoxicillin-clavulanate (Augmentin) is the first-line antibiotic, but excellent alternatives exist for those with allergies. If you notice redness, swelling, or pain after a scratch, don’t wait—see your doctor, start the right antibiotics, and follow care instructions. Quick action can prevent serious complications and ensure a healthy recovery.